Dietary aspartyl-phenylalanine-1-methyl ester delays osteoarthritis and prevents associated bone loss in STR/ORT mice
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چکیده
منابع مشابه
Dietary aspartyl-phenylalanine-1-methyl ester delays osteoarthritis and prevents associated bone loss in STR/ORT mice.
OBJECTIVE STR/ORT mice provide a well-known model for murine idiopathic OA, with histological joint lesions resembling those of human OA. This model was used to investigate protective effects of the dipeptide aspartyl-phenylalanine-1-methyl ester (Asp-Phe-OMe or aspartame) via the oral route vs a regular diet. METHODS STR/ORT mice were housed individually and fed diets with or without Asp-Phe...
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ژورنال
عنوان ژورنال: Rheumatology
سال: 2011
ISSN: 1462-0324,1462-0332
DOI: 10.1093/rheumatology/ker089